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MBBS 'Handwritten to Text' Notes

All the Notes are exclusively handwritten by RB Sah during MBBS days and re-written in to Text for better  reading experience. 

~RB Sah (MBBS, Dr.to Be)


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Pulmonary tb | Classiffication of drugs used in tuberculosis  | first line drugs | second line drugs  | second line newer drugs  | isoniazide | rifampicin | Uses of rifampicin  |

Pulmonary tb is the bacterial infection of the lungs caused by mycobacterium tuberculosis... It can cause various symptoms like chest pain,difficulty in breadthing and severe coughing... Classiffication of drugs used in tuberculosis  1.first line drugs  -isoniazid(H)  -rifampicin(R)  -pyrazinimide(z)  -ethambutol(E)  -streptomycin(S)  2.second line drugs  -thiacetazone(tzn)  -para amino salicylic acide(pASA)  -ethionamide(etm)  -kanamycin(kmc)  -amikacin(am)  -capriyomycin(cpr)  3.second line newer drugs  -ciprofloxacin  -ofloxacin  -azithromycin  -clarithromycin  -rivabutn isoniazide  -first line anti tubercular drugs  -it is bacteriostatic for resting bacili and bactericidal for rapidlly diving organism -act on both extracelluar and intracellular tb bacilli  -MOA (inhibit the synthesis of mycolic acid which is present in the mycobacterial cel wall) -atypical mycobacteria are n...
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Shock | Shock- clinical features | Classification | Cardiogenic shock – |Hypovolemic shock – | Septic shock – | Neurogenic shock-| Anaphylactic shock-  | Pathogenesis of septic shock | Stages of shock | Non-progressive phase- | Progressive stage-  | Irreversible stage- | Morphology | Clinical features of shock |

Contents [hide]  Shock  Definition- Systemic hypoperfusion owing to reduction in either cardiac output or in the effective circulating blood volume. Shock- clinical features Hypotension Tachycardia Cold clammy skin Rapid shallow respiration. Drowsiness.  confusion, irritability Multi organ failure. Classification  Cardiogenic shock –  myocardial pump failure – Intrinsic myocardial damage (infarction), vent. Arrhythmias,  extrinsic comopression (cardiac tamponade) or outflow obstruction (pulmonary embolism). Hypovolemic shock –  loss of blood or plasma volume-  by h’hage, fluid loss from severe burns or trauma. Septic shock –  systemic microbial infection most commonly in gram negative infectns(endotoxic shock) ,can occur with gram +ve & fungal infectns Neurogenic shock- anaesthetic accident or spinal cord injury. Anaphylactic shock-  due to loss of vascular tone & peripheral pooling of blood- IgE mediated response -sys vasodil...
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Vitamins

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